Purpura thrombocitopenike idiopatike në tuberkuloz
DOI:
https://doi.org/10.55312/op.vi1.6225Abstract
Tuberkulozi (TB) është një sëmundje ngjitëse si në vendet në zhvillim ashtu edhe në ato të zhvilluara. Incidenca është në rritje për shkak të bacileve rezistente ndaj shumë barnave dhe virusit të deficitit imunitar human (HIV). Që nga viti 2012, India ka incidencën më të lartë të sëmundjes me rreth 2.2 milionë raste, që përbën 26% të incidencës globale sipas statistikave të Organizatës Botërore të Shëndetësisë. Një spektër i gjerë manifestimesh hematologjike është vërejtur në TB, ku trombocitopenia është e zakonshme në TB miliare dhe trombocitoza në TB pulmonare.Purpura trombocitopenike imune (ITP) karakterizohet nga një numër i ulët i trombociteve i shoqëruar me praninë e autoantitrupave të trombociteve. Lidhja e purpurës trombocitopenike imune dhe tuberkulozit është një gjendje e rrallë. Në rastin e paraqitur , terapia kundër tuberkulozit ishte efektive si për tuberkulozin ashtu edhe për trombocitopeninë, duke sugjeruar një lidhje shkakësore midis tuberkulozit dhe purpurës trombocitopenike imune.
Keywords:
PTI, trombocitopeni, Mycobacterium tuberculosis,, TBC, terapi antituberkulare×Downloads
References
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References
1. Global Tuberculosis Report. Geneva: WHO; 2013. [Accessed 2013 Oct 26]. Annex 2 country profiles;
p. 122. Available from: http://www.who.int/tb/publications/global_report/en/ [Google Scholar]
2. Kashyap R, Chaudhary VP. Haematological manifestations of tuberculosis. In: Sharma SK, Mohan A,
editors. Tuberculosis. Neë Delhi: Jaypee Brothers Medical Publishers (P) Ltd.; 2006. pp. 370–9. [Google
Scholar]
3. Ali R, Ozkalemkas F, Ozçelik T, Ozkocaman V, Ozan U, Kimya Y, et al. Idiopathic thrombocytopenic
purpura in pregnancy: A single institutional experience ëith maternal and neonatal outcomes. Ann Hematol.
2003;82:348–52. [PubMed] [Google Scholar]
4. Liebman HA, Pullarkat V. Diagnosis and management of immune thrombocytopenia in the era of thrombopoietin
mimetics. Hematology Am Soc Hematol Educ Program. 2011;2011:384–90. [PubMed] [Google
Scholar]
5. Boots RJ, Roberts AW, McEvoy D. Immune thrombocytopenia complicating pulmonary tuberculosis:
Case report and investigation of mechanisms. Thorax. 1992;47:396–7. [PMC free article] [PubMed] [Google
Scholar]
6. Ursavas A, Edigar D, Ali R, Koprucuoglu D, Bahcetepe D, Kocamaz G, et al. Immune thrombocytopenia
associated ëith pulmonary tuberculosis. J Infect Chemother. 2010;16:42–4. [PubMed] [Google
Scholar]
7. Ghobrial MË, Albornoz MA. Immune thrombocytopenia: A rare presenting manifestation of tuberculosis.
Am J Hematol. 2001;67:139–43. [PubMed] [Google Scholar]
8. Kalra A, Kalra A, Palanisëamy C, Vikram N, Khilnani GC, Sood R. Immune thrombocytopenia in
a challenging case of disseminated tuberculosis: A case report and revieë of the literature. Case Rep
Med. 2010;2010:pii: 946278. [PMC free article] [PubMed] [Google Scholar]
9. Dagaonkar RS, Udëadia ZF. Disseminated tuberculosis ëith immune thrombocytopenic purpura. Lung
India. 2012;29:63–5. [PMC free article] [PubMed] [Google Scholar]
10. Jurak SS, Aster R, Saëaf H. Immune thrombocytopenia associated ëith tuberculosis. Clin Pediatr
(Phila) 1983;22:318–9. [PubMed] [Google Scholar]
11. Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002;346:995–
1008. [PubMed] [Google Scholar]
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